Studies on Antiviral Therapy that limits the Emergence of HBV Resistance in HIV/HBV Co-infection

Calcutta School of Tropical Medicine0 个研究点目标入组 68 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Study â?? I
•1)Patients above 14 years with documented HIV infection as per NACO guideline along with chronic Hepatitis B
•2)HIV/HBV co-infection of unknown duration with indication of starting ART
•3)Willing to give written informed consent (by self or by guardian in case of < 18 years of age)
•Study â?? II
•1.HBV mono- infected chronic hepatitis patients on 3TC treatment for one year or more.
•2.HIV positive HBV co-infected patients on lamivudine containing ART for at least 1 year
•Study â?? I & II
•1) Blood Parameters
•a.Serum creatinine < 1.5 mg/dl
•2)Negative for Pregnancy test

•1. Active alcohol abuse over last 6 months or > 40 gm/week and any substance use that physician feels can affect the adherence
•2. Presence of associated co-infection with HCV, HAV or HEV
•3. Associated life-threatening disease
•4. Presence of any malignancy
•5.Elevated serum creatinine level > 1.5 mg/dl documented at least twice at one week interval in the last three months

发起方

Calcutta School of Tropical Medicine