In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Intracompartmental Pressure (ICP)
研究概览
简要总结
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.
The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and non-invasively.
The objective is to develop a model mimicking the physiopathology of MCS to assess the interest of the INVOS in this case.
详细描述
After inflation of a tourniquet (pressure equal to the mean arterial pressure, we will obtain a model of slight venous congestion and arterial hypoperfusion. A comparison will be made between INVOS monitoring, sensory deficits, pain, electromyography and invasive pressure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
- •Informed consent
排除标准
- •Neuropathies
- •Vascular pathology
- •Actual pain
- •Anti-platelet or anticoagulant therapy
- •Ipsilateral history of fracture
结局指标
主要结局
Intracompartmental Pressure (ICP)
时间窗: 45 minutes
\[mean (SD)\] ICP (in mmHg), value at baseline and at the time of the block
Comparison Between INVOS Monitoring and Electromyography
时间窗: 45 minutes
A comparison will be made between the INVOS monitoring and non invasive (transcutaneous) EMG monitoring (AP Block), to determine the accuracy of the INVOS monitoring to predict AP block. Measures were: \[mean (SD)\] INVOS (in %) value at baseline and at the time of the block
次要结局
未报告次要终点
研究者
Forget Patrice
MD
Université Catholique de Louvain