Background Incidence of Cardiovascular Ischaemic Events in Treated Parkinson's Disease Patients in the Impact Database
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1
- 主要终点
- Occurrence of CV events during first 6 months
研究概览
简要总结
Cardiovascular (CV) disease is a common comorbidity of Parkinson's disease (PD). The background incidence rate of CV events in a levodopa-treated PD population was assessed to better understand these comorbidities in the PD population. One objective of the study is to identify a population of prevalent PD patients with incident levodopa use within the years 2004-2010 on the Integrated Health Care Information Services (IHCIS) database. The second objective is to report the incidence of CV events overall and during intervals 0-6, 6-12 and 12-18 months after first prescription of levodopa among all new levodopa users.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals with one or more prescriptions of levodopa between 1st July 2004 and 30th June 2010
- •Individuals on the database with medical and pharmacy benefit for at least 6 months prior to date of first prescription of levodopa
- •Individuals with one or more diagnosis codes for Parkinson's disease within the 6 months prior or 6 months post first prescription of levodopa
排除标准
- •Individuals less than 20 years of age on date of first prescription of levodopa
- •Individuals previously prescribed levodopa prior to study period
研究组 & 干预措施
New levodopa users
Individuals with one or more prescriptions of levodopa between 1st July 2004 and 30th June 2010 but no previous levodopa prescriptions prior to study period
干预措施: levodopa (Drug)
结局指标
主要结局
Occurrence of CV events during first 6 months
时间窗: 0-6 months after first prescription of levodopa
Occurrence of CV events during third 6 months
时间窗: 12-18 months after first prescription of levodopa
Overall occurrence of CV events
时间窗: 0-18 months overall after first prescription of levodopa
Occurrence of CV events during second 6 months
时间窗: 6-12 months after first prescription of levodopa
次要结局
未报告次要终点