IRCT20211112053042N2招募中2 期
Evaluation of efficacy and safety of morphine through nebulizer mask in the treatment of acute respiratory distress due to Covid-19 in adult patients
Karaj University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 80 years（—）
- 性别
- All
入选标准
- •Age 80-18 years
- •Patients with a definitive diagnosis of Covid-19 based on PCR test within 48 hours after hospitalization
- •Acute moderate respiratory distress syndrome with PaO2 / FiO2 <200 based on Berlin criteria (Force et al., 2012)
- •Patients with severe dyspnea
- •Patients in the end-stages of the disease
- •Lack of proper treatment
- •Patients with consent to participate in the project
排除标准
- •Patients with high suspicion / diagnosis of heart failure and unstable angina
- •Existence of severe shock with hemodynamic instability despite increased vascular pressure
- •Severe / undiagnosed lung infection for other reasons (chronic obstructive pulmonary disease, pulmonary fibrosis, lung cancer, bacterial pneumonia ...)
- •Diagnosis of pulmonary hemorrhage
- •Pregnancy / breastfeeding
- •An important cause other than acute respiratory distress for respiratory failure
- •Requires ECMO during the study period
- •He/she is expected to be transferred to another hospital within 72 hours
- •Known allergies to morphine
- •Sensitivity or contraindication to exogenous and endogenous opioids
- •Obesity (BMI>35 kg/m2 )
- •Patients with dissatisfaction with participating in the project
研究者
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