NCT04579653撤回不适用
Effects of Various Non-invasion Stimulation Parameters on Pupil Dilation
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Ocular response after transcutaneous nerve stimulation
研究概览
简要总结
This project will apply non-invasive, trans-cutaneous vagal nerve stimulation using various stimulation parameters to young, healthy adults to find the optimal set of parameters to elicit pupil response.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Fluent English speaker with reading and writing proficiency.
排除标准
- •Participants with significant visual impairment or ocular illness may be excluded at the discretion of the principal investigator.
- •Major medical illnesses including severe neurological illness (e.g. stroke, seizure history), autoimmune disorders, and severe psychiatric diseases (e.g., schizophrenia)
- •Any history of brain surgery, tumor, intracranial metal implantation, pacemakers, or other implanted devices.
- •Current (i.e. within 48 hours of the session) prescription medication or over-the-counter medication use.
- •Illicit alcohol or drug use. Caffeine (e.g, coffee, energy drinks) consumption prior to the visit.
研究组 & 干预措施
Group A: Experimental
Experimental
Within-subjects design with a randomization of the order of tVNS administered parameters
干预措施: transcutaneous electrical nerve stimulation devices (Device)
Group B: Active Comparator
Active Comparator
Within-subjects design with a randomization of the order of tVNS administered parameters
干预措施: transcutaneous electrical nerve stimulation devices (Device)
结局指标
主要结局
Ocular response after transcutaneous nerve stimulation
时间窗: Visit 1 day
Number of participants with pupil response after transcutaneous nerve stimulation
次要结局
未报告次要终点
研究者
研究点 (1)
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