Investigate the clinical efficacy and central brain mechanisms of transcutaneous auricular acupoint vagus nerve stimulation in the treatment of patients with insomnia disorder based on multimodal MRI

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

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•1) Conformity to the diagnostic standards of the American Diagnostic and Statistical Manual of Mental Disorders (5th edition) for PI. 2) Insomnia symptoms lasting for > 3 months, =3 times per week. 3) 18 to 70 years old, right-handed. 4) Pittsburgh sleep quality index (PSQI) score=8,17 items of the Hamilton Depression Scale =17 and 14 items of the Hamilton Anxiety Scale =14. 5) Not taking any neuropsychiatric medications or substances and not receiving acupuncture treatment in the past month. 6) Cooperate to accept the treatment of auricular electrical stimulation and complete the acquisition of magnetic resonance data. 7) Signed the informed consent form..

•1) Patients with severe physical diseases, such as coronary heart disease, malignant tumor and renal failure. 2) Patients with brain organic diseases. 3) Combined with any other mental disorder, personality disorder or psychoactive substance abuse or dependence. 4) Patients who cannot elute from medicine or acupuncture treatment. 5) Pregnant and lactating women. 6) Patients with contraindications of magnetic resonance imaging (MRI). 7)Patients with damaged ear skin. 8)Patients who were unwilling to sign inform consent.

发起方

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences