The Effects of Top Set Training in Combination With Power Training in Subjects With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Change in neuromuscular performance as measured by power production.
研究概览
简要总结
This project will focus on improving power in adults with Parkinson's disease, since power is related to performance of daily activities and memory and decision making. The study will compare traditional power training, where the participant does all exercises as fast as possible to top set resistance training, where the participant does power training, but it is preceded by warm-up sets that progress in weight until the participant reaches 90% of the person's maximum strength. If the top set method is better than traditional power training, it could be more beneficial than existing methods in improving independence in adults with Parkinson's disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of Parkinson's disease
- •Between the ages of 30-90 years of age
- •A Hoehn and Yahr score of ≤3, which will be provided by the participant's medical provider within 1 year of the study's inception.
排除标准
- •Uncontrolled cardiovascular disease that prevents participation in a training program
- •Documented HIV infection or another immunodeficiency syndrome
- •Other neuromuscular diseases besides Parkinson's disease
- •Current musculoskeletal injury that prevents exercise.
- •Having a pacemaker
- •Pregnancy
- •Incarcerated individuals
- •Montreal Cognitive Assessment Score below 18
结局指标
主要结局
Change in neuromuscular performance as measured by power production.
时间窗: Baseline, 12 weeks
This test measures the power a person can produce at maximal speed using a load of 50% of 1RM for the chest press and leg press. There are no minimum or maximum scores. The higher score indicates higher power. Power shows how fast a person can do work. The test typically takes about five minutes. Unit of measure is Watts.
Change in neuromuscular performance as measured by 1-repetition maximum (1RM
时间窗: Baseline, 12 weeks
Maximal load that can be lifted in one repetition (1RM) will be assessed for in both leg press and chest press exercises. The loads on the testing equipment will be increased over 5 to 7 testing sets. The persons 1RM will be the highest load the person can move through the range of motion of the exercise. There are no minimum or maximum scores for this test. The test typically takes 5 to 10 minutes. The higher the 1RM the stronger the person is.
次要结局
- Change in the Speed of the Ten-Meter Walk Test.(Baseline, 12 weeks)
- Changes in Swing time of Gait.(Baseline, 12 weeks)
- Changes in Stance Time of Gait.(Baseline, 12 weeks)
- Changes in Speed of Gait.(Baseline, 12 weeks)
- Changes in Stride Width of Gait.(Baseline, 12 weeks)
- Changes in Double Support Time of Gait.(Baseline, 12 weeks)
- Changes in Step Time of Gait.(Baseline, 12 weeks)
- Changes in Cadence of Gait.(Baseline, 12 weeks)
- Changes in Stride Length of Gait.(Baseline, 12 weeks)
- Changes in Step Length of Gait.(Baseline, 12 weeks)
- Change in Time for the Five Times Sit-to-Stand Test.(Baseline, 12 weeks)
- Change in Distance of the Seated Medicine Ball Throw.(Baseline, 12 weeks)
- Changes in the Six-Minute Walk Test(Baseline, 12 weeks)
- Change in the time required to complete the Timed Up-and-Go Test.(Baseline, 12 weeks)
- Change in Muscle Thickness using Ultrasound.(Baseline, 12 weeks)
- Change in Muscle Quality using Gray Scale.(Baseline, 12 weeks)
- Changes in the Parkinson's Disease Questionnaire.(Baseline, 12 weeks)
研究者
Joseph Signorile
Professor
University of Miami