The Acute, Synergistic Effects of Protein and Calcium on Appetite and Energy Intake
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Energy Intake
研究概览
简要总结
High-protein meals have previously been shown to acutely reduce appetite and energy intake. More recently, meals higher in calcium have also been shown to increase feelings of fullness, circulating insulin and intestinal peptide concentrations and reduce appetite sensations.
This study aims to assess whether calcium and protein act synergistically to acutely influence appetite and energy intake.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or Female
- •BMI 18.5-29.9 kg/m2
- •Age: 18-40 years
排除标准
- •Food allergies
- •Metabolic disorders (ie. type 2 diabetes)
研究组 & 干预措施
CONTROL
Control breakfast low in protein and calcium. Porridge-based breakfast.
干预措施: Porridge-based breakfast. (Dietary Supplement)
PROTEIN
High-protein breakfast.
干预措施: Protein (Dietary Supplement)
PROTEIN
High-protein breakfast.
干预措施: Porridge-based breakfast. (Dietary Supplement)
CALCIUM
High-calcium breakfast.
干预措施: Porridge-based breakfast. (Dietary Supplement)
PRO-CAL
High-protein and calcium breakfast.
干预措施: Protein (Dietary Supplement)
PRO-CAL
High-protein and calcium breakfast.
干预措施: Porridge-based breakfast. (Dietary Supplement)
PRO-CAL
High-protein and calcium breakfast.
干预措施: Calcium (Dietary Supplement)
CALCIUM
High-calcium breakfast.
干预措施: Calcium (Dietary Supplement)
结局指标
主要结局
Energy Intake
时间窗: 60 min post test-meal
Energy intake will be assessed by ad libitum consumption of a homogenous pasta meal, 1 h after the test-meal.
次要结局
- Subjective appetite sensations(1 hr)
- Insulin concentrations(1 hr)
- GLP-1 (7-36) concentrations(1 hr)
- GIP concentration(1 hr)
研究者
Javier Gonzalez, PhD
Research Fellow
Northumbria University