Improved Prediction of Clinical Outcome With the Use of Global Strain and Mechanical Dispersion in Patients With Myocardial Infarction and Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,100
- 试验地点
- 8
- 主要终点
- Ventricular arrhythmia and death after acute myocardial infarction or heart failure.
研究概览
简要总结
The aim of the study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than ejection fraction(EF) in patients with myocardial infarction and heart failure regardless of cause.
详细描述
- The main aim of this study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than left ventricular ejection fraction in patients with myocardial infarction and heart failure.
- In patients who receive internal cardioverter defibrillator(ICD) the main aim is to investigate if mechanical dispersion may predict ventricular arrhythmias better than EF.
-
No interventions,only evaluation of the measurements obtained with transthoracic echocardiography.
-
Follow up for 3 years, extended from 3 to 5 years.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with
- •myocardial infarction
- •heart failure( defined as heart failure symptoms: reduced left ventricular function/ and or heart failure signs on chest x ray.
- •planned for primary prophylactic ICD
- •over 18 years of age
- •Informed consent
排除标准
- 未提供
结局指标
主要结局
Ventricular arrhythmia and death after acute myocardial infarction or heart failure.
时间窗: 5 years or more
Arrhythmic events during follow-up are defined as documented sustained ventricular tachycardia, ventricular fibrillation, and SCD. Survival is assessed by medical charts if patients are within the uptake area of the hospital and by the Norwegian death registry Folkeregisteret.
次要结局
未报告次要终点
研究者
Thor Edvardsen
Professor, Chief department of Cardiology Oslo university hospital
Oslo University Hospital