Micro- and Macro-Circulation in Cardiac Surgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Prediction of major morbidities by means of the variability of cardiovascular and hemodynamics markers
研究概览
简要总结
The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major morbidities (stroke, acute kidney injury, prolonged intubation, mediastinitis, surgical reopening, death).
The state of sublingual microcirculation, of peripheral microcirculation and cardiovascular control will be assessed in 100 patients undergoing cardiac surgery during general anesthesia before the intervention and at the end of the intervention at the arrival in post-surgery ICU by means of signal processing techniques.
The extracted markers will be used to assess a statistical prediction model of major morbidities.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age >18 yrs
- •indication for a cardiac surgery intervention
- •spontaneous sinus rhythm
- •informed consent
排除标准
- •know autonomic nervous systems pathologies or dysfunctions
- •pregnancy
结局指标
主要结局
Prediction of major morbidities by means of the variability of cardiovascular and hemodynamics markers
时间窗: 24 months
Statistical model assessment; time series variability analysis
次要结局
未报告次要终点
研究者
Vlasta Bari
Assistant Professor, PhD
IRCCS Policlinico S. Donato