Comparison of Magnesium Sulphate and Fentanyl as an Adjuvant to Ropivacaine in Intravenous Regional Anaesthesia for Upper Extremity Surgeries-A Prospective Randomised Double Blind Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.To assess the onset and duration of motor & sensory blockade
研究概览
简要总结
Regional anaesthesia may provide an ideal and safe operative condition when used optimally. It is said to cause the least interference with the vital physiological functions of the body with reduced stress response, avoids polypharmacy and provides an alert, awake and co-operative patient when compared to conventional methods. The adequately administered regional anaesthesia provides excellent intraoperative pain control and also good relief of postoperative pain & regional blocks are less stressful for the patients.Intravenous regional anesthesia (IVRA) is used in Outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages and it is an ideal anesthetic method particularly for short lasting procedures.Ropivacaine may serve as local anaesthetic for IVRA that could provide prolonged and improved analgesia over lidocaine and have lower toxicity profile when compared with bupivacaine. In an attempt to reduce tourniquet discomfort and pain and to improve the postoperative analgesia, adjuvants could be added. It is giving good analgesia and adequate muscle relaxation. Provides bloodless operative field. Widely applicable to patients of different ages and physical status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patient with ASA physical status 1 & 2 Age from 18yrs to 60 yrs.
排除标准
- •1.known allergies to the drugs used.
- •2.patient belonging to ASA 3 & above 3.Patients with a history of any Cardiovascular, respiratory, or central nervous system disorder 4.Patients with hematological disorders such as sickle cell anemia and thalassemia.
- •5.patient with difficult airway.
结局指标
主要结局
1.To assess the onset and duration of motor & sensory blockade
时间窗: from the time of drug injection to pin prick sensation checked at six separate areas | inability to move fingers and elbow in supine position after drug injection
2.To assess time to first postoperative analgesic requirement.
时间窗: from the time of drug injection to pin prick sensation checked at six separate areas | inability to move fingers and elbow in supine position after drug injection
次要结局
- To assess time to first postoperative analgesic requirement.(recovery from sensory and motor block)