Evaluation of Irrigation Effectiveness for Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Logarithmic reduction of bacterial count within the root canal of activated chlorhexidine solution.
研究概览
简要总结
The process of removing bacteria and their products from the root canals is an essential step that is achieved through the combination of mechanical preparation and irrigation with chemicals. However, mechanical preparation alone can not reduce the microbial formations inside root canals, so at least about 35% of the root canal walls remain without the preparation tools reaching them.
Many irrigants were used to irrigate the root canals, as sodium hypochlorite and chlorhexidine are the most famous. Although most studies have proven the effectiveness of sodium hypochlorite with its different concentrations in accomplishing this task, some of them showed the inability of the irrigant fluid to eliminate Enterococcus faecalis inside the canals. These bacteria are highly resistant, and therefore endodontic treatment fails in the long term.
详细描述
Bacteria and their products play an essential role in the initiation and persistence of endodontic diseases. Therefore, eliminating them and preventing the return of their effectiveness is the desired goal in any successful endodontic treatment in the short and long term.
Due to the fact that mechanical preparation of the root canal alone is not capable of removing the entire bacterial content, chemical irrigants were considered necessary to reduce the number of bacteria and toxins resulting from them. Until now, there is no irrigant capable of removing the entire bacterial content from the root canal.
Despite the many advantages of sodium hypochlorite, several studies have revealed the toxicity of the solution in high concentrations of it, and it tends to cause tissue irritation when it comes into contact with the apical tissues.
Chlorhexidine has been used for a long time in dentistry due to its antibacterial properties, long period of effect, and relatively low toxicity. This has prompted its use as an irrigant and an intra-canal dressing in endodontic treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 4 Years 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Definitely positive or positive ratings of Frank scale.
- •Physiological root resorption no more than the apical third
- •Symptoms or signs of pulpal necrosis with or without radial lesions (swelling - fistua - abnormal movement).
- •At least 2 mm of bone surrounding the permanent bud.
- •Children who have not taken antibiotics in the past 3 months.
排除标准
- •Systematic or mental disorders.
- •Definitely negative or negative ratings of Frankel scale
- •Existence external or internal abnormal absorption.
结局指标
主要结局
Logarithmic reduction of bacterial count within the root canal of activated chlorhexidine solution.
时间窗: 24 hours after sample incubation
Set the Petri dish on a grid background and count the colonies in each grid cell, moving in a methodical pattern through all of the cells.
Logarithmic reduction of bacterial count within the root canal of sodium hypochlorite solution.
时间窗: 24 hours after sample incubation
Set the Petri dish on a grid background and count the colonies in each grid cell, moving in a methodical pattern through all of the cells.
Logarithmic reduction of bacterial count within the root canal of chlorhexidine gel.
时间窗: 24 hours after sample incubation
Set the Petri dish on a grid background and count the colonies in each grid cell, moving in a methodical pattern through all of the cells.
Logarithmic reduction of bacterial count within the root canal of chlorhexidine solution.
时间窗: 24 hours after sample incubation
Set the Petri dish on a grid background and count the colonies in each grid cell, moving in a methodical pattern through all of the cells.
Logarithmic reduction of bacterial count within the root canal of activated chlorhexidine gel.
时间窗: 24 hours after sample incubation
Set the Petri dish on a grid background and count the colonies in each grid cell, moving in a methodical pattern through all of the cells.
次要结局
未报告次要终点