Psycho-biological substrates of therapeutic benefit of thermal cure on Generalized Anxiety Disorders - Insula-TOP

Centre Hospitalier Henri Laborit0 个研究点开始时间: 2016年2月26日最近更新: 2017年4月3日

适应症

试验速览

暂无简介。

•Diagnostic of TAG according to DSM IV
•No treatment by antidepressant for at least 2 months
•No treatment by anxiolytic/neuroleptic/bete blockers/antipsychotic for at least 3 weeks
•Global score of HAMA is greater or equal to 20
•Score of HAMA symptoms greater or equal to 8
•Score of HAMD lower or equal to 7
•Age: Participants will be males and females, 18-75 years of age included.
•For women, no ongoing pregnancy/ negative pregnancy test
•No wounds
•Affiliation to a social security system (recipient or assignee)
•Signed written inform consent form
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 50
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 10

•Treatment by antidepressant for at least 2 months or a treatment by anxiolytic, neuroleptic for at least 3 weeks
•Psychotropic treatment (antidepressant, anxiolytic and neuroleptic) between the preinclusion and inclusion
•Psychotherapy during the 3 months prior to the inclusion
•Thermal cure during the 6 months prior to the inclusion
•Treatment by paroxetine (Deroxat® ou Divarius®) for at least 1 month with dose equal or superior to 20 mg per day during the 12 months prior to the inclusion
•Contraindication to paroxetine
•Enhanced protection (minors, pregnancies women, nursing women, , people Deprived of liberty by administrative or judicial decision, ...)
•Blood donation during the 3 months prior to the inclusion

发起方