TCTR20230826008招募中1 期
Root coverage outcomes and viability of subepithelial connective tissue grafts harvesting from palate before and after recipient site preparation.
Faculty of Dentistry, Mahidol University0 个研究点目标入组 40 人开始时间: 2023年8月26日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)(—)
- 性别
- All
入选标准
- •-Age more than 18 years old who needs a periodontal soft tissue graft treatment
- •-No contra-indicatory to the surgery
- •-Single gingival recession at buccal sites of single root teeth classified as RT1 or RT2 by Cairo, 2011
- •-Good inflammation control (full-mouth bleeding on probing less than 25%)
- •-Good plaque control (full-month plaque score less than 25%)
- •-Probing depth less than 4 mm at an interesting site
- •-No history of periodontal surgery at the recipient site
- •-Age more than 18 years old who needs a periodontal soft tissue graft treatment
- •-No contra-indicatory to the surgery.
排除标准
- •- Patients who have medical contraindications to periodontal surgery
- •- Taking antibiotics or drugs affecting periodontal healing within 6 months.
- •- Excessive tooth mobility on the surgical site
- •- Recession defect with restoration/demineralization/caries/deep abrasion or abfraction >1mm or evidence of pulpal pathology
- •- Patients who have medical contraindications to periodontal surgery
- •- Patients who have a disease or syndrome and receive medications that affect the quantity of saliva, inflammation phase, and healing process. These include the patients who are diagnosed with xerostomia or Sjogren's syndrome; patients who take chemotherapy drugs, antiresorptive drugs, antiangiogenics drugs, steroid drugs, anti-inflammatory drugs (depending on the type of drugs, e.g., ibuprofen is eliminated in 24 hours, thus patients who take ibuprofen >24 hours before the surgery can be included), antibiotic drugs in past 6 months, immunosuppressive drugs, amphetamine/methamphetamine drugs; and patients who currently use marijuana or a current smoker.
- •- The biopsy site has inflamed gingival tissue (redness, swelling, or bleeding), involves an important organ at the palate, or presents any pathologic oral lesions.
- •- The patients undergo a soft tissue graft harvesting but the harvesting site is insufficient for another 4-mm diameter 2-mm thick biopsy sample, e.g., the area is closed to some vital structures, thin palatal tissue < 2 mm.
研究者
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