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临床试验/TCTR20230826008
TCTR20230826008招募中1 期

Root coverage outcomes and viability of subepithelial connective tissue grafts harvesting from palate before and after recipient site preparation.

Faculty of Dentistry, Mahidol University0 个研究点目标入组 40 人开始时间: 2023年8月26日最近更新:
适应症

试验速览

阶段
1 期
状态
招募中
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 N/A (No limit)(—)
性别
All

入选标准

  • -Age more than 18 years old who needs a periodontal soft tissue graft treatment
  • -No contra-indicatory to the surgery
  • -Single gingival recession at buccal sites of single root teeth classified as RT1 or RT2 by Cairo, 2011
  • -Good inflammation control (full-mouth bleeding on probing less than 25%)
  • -Good plaque control (full-month plaque score less than 25%)
  • -Probing depth less than 4 mm at an interesting site
  • -No history of periodontal surgery at the recipient site
  • -Age more than 18 years old who needs a periodontal soft tissue graft treatment
  • -No contra-indicatory to the surgery.

排除标准

  • - Patients who have medical contraindications to periodontal surgery
  • - Taking antibiotics or drugs affecting periodontal healing within 6 months.
  • - Excessive tooth mobility on the surgical site
  • - Recession defect with restoration/demineralization/caries/deep abrasion or abfraction >1mm or evidence of pulpal pathology
  • - Patients who have medical contraindications to periodontal surgery
  • - Patients who have a disease or syndrome and receive medications that affect the quantity of saliva, inflammation phase, and healing process. These include the patients who are diagnosed with xerostomia or Sjogren's syndrome; patients who take chemotherapy drugs, antiresorptive drugs, antiangiogenics drugs, steroid drugs, anti-inflammatory drugs (depending on the type of drugs, e.g., ibuprofen is eliminated in 24 hours, thus patients who take ibuprofen >24 hours before the surgery can be included), antibiotic drugs in past 6 months, immunosuppressive drugs, amphetamine/methamphetamine drugs; and patients who currently use marijuana or a current smoker.
  • - The biopsy site has inflamed gingival tissue (redness, swelling, or bleeding), involves an important organ at the palate, or presents any pathologic oral lesions.
  • - The patients undergo a soft tissue graft harvesting but the harvesting site is insufficient for another 4-mm diameter 2-mm thick biopsy sample, e.g., the area is closed to some vital structures, thin palatal tissue < 2 mm.

研究者

发起方
Faculty of Dentistry, Mahidol University

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