Prospective, Nasal Specimen Collection Study in Patients Presenting With Influenza Like Illness and/or Acute Respiratory Infection in an Outpatient Setting
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Nasal swab collection of left and right nostril
研究概览
简要总结
This is a prospective specimen collection study targeting patients presenting with Influenza Like Illness (ILI) and/or Acute Respiratory Infection (ARI) in an out-patient setting. A non-invasive, user friendly sampling technique, using midturbinate flocked swabs will be used. These nasal swabs will be collected in different volumes of viral transport media (0.5mL and 3.0mL), for different dilution range of the viruses present in the collected biological specimen. The collection of nasal swabs samples will support the optimization of point of care detection methods for respiratory viruses responsible for ILI and/or ARI.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or Female
- •Valid Informed Consent and/or Assent, where applicable
- •Onset of ILI and/or ARI within the last 3 days (≤ 72h)
- •Patient presented with ILI and/or ARI
排除标准
- •Invalid Informed Consent and/or Assent
- •Onset of ILI and/or ARI was > 3 days (> 72 h)
- •Patient did not presented with neither ILI or ARI
- •Patient received intranasal attenuated influenza virus in last 3 weeks (example FluMist®, Fluenz®)
- •Patient received treatment with influenza direct antivirals in the last 7 days
结局指标
主要结局
Nasal swab collection of left and right nostril
时间窗: 1 day
At the moment volunteer presents him/herself to the general practioner with influenza-like-illness
次要结局
- Completion of questionnaire(1 day)
研究者
Lieselot Houspie
PhD student Laboratory of Clinical Virology
Universitaire Ziekenhuizen KU Leuven