跳至主要内容
临床试验/NCT04422158
NCT04422158已完成不适用

Impact of Nuun Electrolyte Tablets on Hydration Status in Active Men and Women: Single-blinded Study

University of Memphis1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年6月3日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Body weight

研究概览

简要总结

The purpose of this study is to determine the impact of Nuun electrolyte tablets on hydration status in young and active men and women. We will follow a similar approach as used by Maughan and colleagues (2016) to measure the beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water). It is hypothesized that Nuun electrolyte tablets will result in a greater hydration status as compared to water only. Due to the fact that athletes use Nuun tablets at varying dosages, we will evaluate Nuun at both a single dosage and a double dosage. We maintain a non-directional hypothesis regarding the potential differences between the two different dosages tested.

详细描述

Maintaining adequate hydration is essential to optimal health and athletic performance. When individuals exercise (in particular in a warm environment), they can lose excessive amounts of fluids through sweating, along with necessary electrolytes (e.g., sodium, potassium, chloride). With dehydration, individuals may feel sluggish and can experience impaired physical performance.

Many attempts have been made to improve and measure the hydration status of active individuals. This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage). This approach seems to work well; however, some debate remains over what the best fluid is to consume, in particular related to the macronutrient type and the specific electrolyte mix.

Related to the above, it is well-accepted that electrolyte replenishment is of importance, both during and following exercise-to aid in rehydration for subsequent bouts. The use of electrolytes (sodium in particular) has been used for decades to aid athlete hydration and has led to the development of various sport drinks-which also include small amounts of carbohydrate. However, one problem with carbohydrate ingestion is that some individuals experience gastrointestinal (GI) upset following carbohydrate ingestion before and during an event, despite very good physical performance outcomes. Due to this GI upset, some individuals (in particular recreationally active individuals who are not competing at high levels) rely solely on water and seek a method to ingest the lost electrolytes. In addition, some individuals prefer to have both plain water and an electrolyte beverage during their training/competition sessions and in some activities (e.g., running, cycling), carrying multiple bottles of fluid is difficult.

The solution to the above issues for many athletes is the use of electrolyte tablets. These can be dropped into plain water and will dissolve into a flavored electrolyte-rich beverage. They are easy to transport and provide the needed electrolytes to replace those that are lost through intense and/or long duration exercise.

Nuun electrolyte tablets provide only 2 grams of carbohydrate and a combination of electrolytes, provided at a relatively low percentage of the Daily Value (DV). The DV tells us how much a particular nutrient in a serving of a food product contributes to a daily diet, based on a standard 2000 calorie diet. Nuun tablets contain: calcium (13mg, 1%DV), sodium (300mg, 13%DV), potassium (150mg, 3%DV), magnesium (25mg, 6%DV), and chloride (40mg, 2%DV). These tablets contain a small percentage of the needed total electrolytes but adequate amounts to replace lost electrolytes as a result of physical activity.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

盲法说明

Drinks will be prepared without subjects aware of which drink they are receiving.

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •BMI between 18.5 and 29.9 kg/m2 (not obese)
  • •Consumes 2 liters of water daily
  • •Exercised 3 hours/week over the past 6 months

排除标准

  • •Pregnant or trying to become pregnant
  • •Tobacco user
  • •Cardiac Disease
  • •Consumed alcohol within 48 hours of testing visit
  • •Consumed caffeine within 48 hours of testing visit
  • •Strenuous excercise 24 hours prior to testing visit

研究组 & 干预措施

Control

Placebo Comparator

Subjects will drink one liter of water over 30 min (250 mL every 7.5 min)

干预措施: water (Other)

Nuun Single strength

Experimental

3 Nuun electrolyte tablets will be dissolved in 1.4 liters of water. Subjects will drink one liter of the prepared solution over 30 min (250 mL every 7.5 min)

干预措施: Nuun electrolyte tablet (Dietary Supplement)

Nuun Double strength

Experimental

6 Nuun electrolyte tablets will be dissolved in 1.4 liters of water. Subjects will drink one liter of the prepared solution over 30 min (250 mL every 7.5 min)

干预措施: Nuun electrolyte tablet (Dietary Supplement)

Nuun Double strength

Experimental

6 Nuun electrolyte tablets will be dissolved in 1.4 liters of water. Subjects will drink one liter of the prepared solution over 30 min (250 mL every 7.5 min)

干预措施: water (Other)

Nuun Single strength

Experimental

3 Nuun electrolyte tablets will be dissolved in 1.4 liters of water. Subjects will drink one liter of the prepared solution over 30 min (250 mL every 7.5 min)

干预措施: water (Other)

结局指标

主要结局

Body weight

时间窗: 4 hours after drink consumption

Body weight will be measured

Urine volume

时间窗: 4 hours after intervention

Volume of urine output will be measured

Urine mass

时间窗: 4 hours after intervention

Urine output will be measured using a scale

Heart Rate

时间窗: 4 hours after intervention

Heart Rate will be measured

Blood Pressure

时间窗: 4 hours after intervention

Blood pressure will be measured.

Blood Pressure

时间窗: at baseline

Blood pressure will be measured.

Body weight

时间窗: baseline

Body weight will be measured

Urine volume

时间窗: Immediately after completing intervention

Volume of urine output will be measured

Urine volume

时间窗: 1 hour after intervention

Volume of urine output will be measured

Urine volume

时间窗: 2 hours after intervention

Volume of urine output will be measured

Urine volume

时间窗: 3 hours after intervention

Volume of urine output will be measured

Urine mass

时间窗: Immediately after completing intervention

Urine output will be measured using a scale

Urine mass

时间窗: 1 hour after intervention

Urine output will be measured using a scale

Urine mass

时间窗: 2 hours after intervention

Urine output will be measured using a scale

Urine mass

时间窗: 3 hours after intervention

Urine output will be measured using a scale

Blood Pressure

时间窗: 1 hour after intervention

Blood pressure will be measured.

Blood Pressure

时间窗: 2 hours after intervention

Blood pressure will be measured.

Blood Pressure

时间窗: 3 hours after intervention

Blood pressure will be measured.

Heart Rate

时间窗: baseline

Heart Rate will be measured

Heart Rate

时间窗: 1 hour after intervention

Heart Rate will be measured

Heart Rate

时间窗: 2 hours after intervention

Heart Rate will be measured

Heart Rate

时间窗: 3 hours after intervention

Heart Rate will be measured

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Bloomer

Dean of School of Health Studies

University of Memphis

研究点 (1)

Loading locations...

相似试验