Epidemiology of Celiac Disease: A Prospective Study of Undiagnosed Celiac Disease in the Community
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 31
- 试验地点
- 2
- 主要终点
- Understanding the impact of undiagnosed celiac disease and the potential benefits of diagnosis
研究概览
简要总结
Direct benefits to the participants, who are diagnosed with celiac disease may be substantial and could include lessening or prevention of GI symptoms, correction of biochemical abnormalities and reduction in risk for malignancies or bone disease which are most common in untreated celiac disease. However, the precise benefit is unknown and the motivation for this proposed study. If these individuals have a positive celiac serology test at the present time there is a high likelihood that they may have celiac disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least 60 years old
- •Male and female
- •Retrospective testing for celiac disease was done on previously stored serum. Contacting specific individuals for inclusion into study
排除标准
- 未提供
研究组 & 干预措施
Dietary instruction on Gluten Free Diet
干预措施: Dietary instruction (Other)
结局指标
主要结局
Understanding the impact of undiagnosed celiac disease and the potential benefits of diagnosis
时间窗: one year
To understanding the impact of undiagnosed celiac disease and the potential benefits, detection and treatment may have a substantial impact on the health of these subjects and the large numbers of Americans with undiagnosed celiac disease. The outcome measures we will be looking at are Quality of Life, GI Symptoms including diarrhea, constipation, abdominal pain, Tissue Transglutaminase level improvement after 12 weeks on a gluten free diet, bone density, understanding of a gluten free diet.
次要结局
未报告次要终点
研究者
Joseph A. Murray, M.D.
Professor of Medicine
Mayo Clinic