Evaluation of Fatigue and Mitigations During Long-haul Operations
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 118
- 试验地点
- 1
- 主要终点
- Vigilant Attention
研究概览
简要总结
The purpose of the present study is to test novel countermeasures to reduce fatigue among airline pilots during long-haul flight operations. The investigators will collect objective and subjective sleep, sleepiness, workload, and performance data from active-duty line pilots flying long-haul flight operations (>8 hours). Data will be collected during days off prior to the trip start, during flights and layover, and during days off following the trip end.
详细描述
This study will evaluate whether a calorie restriction and lighting countermeasure are capable of improving performance and reducing fatigue and sleepiness among commercial airline pilots during trips that involve long-haul (LH) overnight operations. All participants will collect data for two LH trips that involve overnight flying, and for three days before and after each trip. All participants will collect baseline data for one trip with no intervention. Upon completion of the baseline trip, participants will be randomized to receive the intervention or control for a future similar trip. The intervention will involve asking pilots to reduce their calorie intake during the biological night to < 10% of their daily need and to wear blue-enriched light emitting glasses for 20 minutes following their inflight rest break before they return to the flight deck. The control condition will involve reminding pilots about standard fatigue risk management practices that are recommended by their company.
Specific Aims: The aim of this study is to determine whether a calorie restriction and lighting intervention will improve alertness and performance during LH flight operations compared to standard fatigue risk management practices among pilots flying LH overnight operations during outbound and return flights.
Hypotheses:
We hypothesize that:
- pilot alertness, fatigue, mood, and performance at top of descent (TOD) will be better among pilots randomized to limit their overnight calorie intake to a small snack (<10% daily calorie needs) compared to those who are not provided with guidance on calorie restriction.
- pilot alertness, fatigue, mood, and performance following their inflight rest break will be better following exposure to blue-enriched lighting compared to no blue-enriched lighting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All medically qualified, active-duty pilots currently flying overnight long-haul operations are eligible to be included as participants in the study. Participants must be line pilots that spend at least 50% of their typical monthly schedule flying long-haul operations (defined at flights over eight hours induration).
排除标准
- •Pilots with metabolic disorders, such as diabetes, those actively trying to lose weight or receiving GLP-1 injections, or those who indicate that they are sensitive to light will be excluded from participation. The medical monitor will review the pilot's self-reported medical conditions and medications (if applicable) prior to enrolment in the study.
研究组 & 干预措施
Intervention (caloric restriction and light intervention)
The intervention will involve asking pilots to reduce their calorie intake during the biological night to < 10% of their daily need and to wear blue-enriched light emitting glasses for 20 minutes following their inflight rest break before they return to the flight deck during both outbound and return flights
干预措施: Caloric restriction (Behavioral)
Intervention (caloric restriction and light intervention)
The intervention will involve asking pilots to reduce their calorie intake during the biological night to < 10% of their daily need and to wear blue-enriched light emitting glasses for 20 minutes following their inflight rest break before they return to the flight deck during both outbound and return flights
干预措施: Light exposure (Device)
Control
The control condition will involve reminding pilots about standard fatigue risk management practices that are recommended by their company.
结局指标
主要结局
Vigilant Attention
时间窗: minimum of 18 days, morning, afternoon, evening and top of descent of all flights
Measured using the 5-minute Psychomotor Vigilance Task (PVT); a simple reaction time test with measures that include mean reaction time, response speed (1/RT), and number of lapses (RT \> 500ms).
Subjective Sleepiness
时间窗: Minimum of 18 days, morning, afternoon, evening and top of descent of all flights
Measured using the Karolinska Sleepiness Scale (KSS); a 9-point Likert scale with higher scores indicating higher levels of sleepiness.
Subjective Fatigue
时间窗: minimum of 18 days, morning, afternoon, evening and top of descent of all flights
Measured using the Samn-Perelli fatigue scale; a 7-point Likert scale with higher scores indicating higher levels of fatigue
Objective Sleep
时间窗: 24 hours a day for a minimum of 18 days
Measured using an accelerometer (wristwatch-like device) and light sensor to determine sleep and wake patterns and various other objective sleep metrics (e.g., sleep onset, wake after sleep onset, total sleep time).
次要结局
未报告次要终点
研究者
Erin E. Flynn-Evans
Laboratory Director
National Aeronautics and Space Administration (NASA)