Comparison of DNA Image Cytometry and Conventional Cytology for Cervical Cancer Screening in China
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- The incidence of cervical cancer.
研究概览
简要总结
Very few screenings of any kind will be possible during a woman's lifetime in most low-resource regions, where 80% of the half-million global cases of cervical cancer occur every year. Although a single round of human papillomavirus (HPV) testing was associated with a significant decline in the rate of advanced cervical cancers and associated deaths, whether other methods like as DNA image cytometry can be used as an more accurate means than others in screening cervical cancer or not is yet to be verified. In addition, the accuracy of both DNA image cytometry and conventional cytology is not well known. The investigators hypothesized that DNA image cytometry was superior in screening cervical cancer than conventional cytology.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Currently or had been married
- •Not pregnant
- •Had an intact uterus with no prolapse
- •Had no history of cervical cancer
- •Living in China
排除标准
- •Not willing to participate or finish the study at any time
- •History of cervical surgeries
结局指标
主要结局
The incidence of cervical cancer.
时间窗: From the testing performed by the investigator (0h) to one year follow-up period
次要结局
- The rate of death.(One year follow-up period after screening.)
- The incidence of cervical intraepithelial neoplasia.(From the screening (0h) to one year follow-up period)
- Cervical inflammation(From the screening (0h) to one year follow-up period)