IRCT2015072123282N1已完成未知
Evaluation of the effect of Elaeagnus angustifolia alone and in combination with Boswellia thurifera compared with ibuprofen in patients with knee osteoarthritis
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 75
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40 years 至 80 years(—)
- 性别
- All
入选标准
- •age of 40 - 80 years; Osteoarthritis of at least one knee for at least 6 months based on the diagnostic criteria of American College of Rheumatology (ACR); Pain score > 40 mm based on the visual analogue scale (VAS); CRP serum level < 10 mg/dL; LPFI (Lequesne Pain and Function Index) score > 7; Grade 2 or 3 of Kellgren-Laurence scale in knee radiography within the past 6 months
- •Exclusion criteria: Dysfunction of either liver, kidneys, or cardiovascular system or malignancy; Use of intra-articular glucocorticoids within the past 3 months; Use of intra-articular sodium hyaluronate within the past 6 months; Use of systemic glucocorticoids (either oral or parenteral) within the past 3 months; Having other osteoarticular disorders (e.g., rheumatoid arthritis and gout); Uncontrolled hypertension (> 140/90 mm Hg); Increased ESR; Having gastric or duodenal ulcers (based on the medical history); Sensitivity to the intervention drug; Being candidate for arthroplasty surgery; Not use of the intervention drug for more than one week; Knee arthroscopy within the past 3 months; Illiteracy
排除标准
- 未提供
研究者
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