Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Basic Autonomic Nervous System Activity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- Systolic Blood Pressure
研究概览
简要总结
Transcutaneous Auricular Vagus nerve stimulation may be successful in cardiac modulation because of the cardiac connections of the vagal nerve. Therefore, in order to observe the cardiac effects, it was analysed the changes in pulse rate, systolic and diastolic blood pressure after transcutaneous auricular vagus nerve stimulation application.
详细描述
Participants were divided into four groups (Figure 1) according to PNS and SNS indexes as Group 1 (PNS index <-2, SNS index >+2), Group 2 (PNS index <-2, SNS index <+2), Group 3 (PNS index >-2, SNS index >+2), Group 4 (PNS index >-2, SNS index <+2). Participants were assessed with blood pressure, pulse rate and HRV before and after taVNS stimulation. Sympathetic nervous system (SNS) index and parasympathetic nervous system (PNS) index values were assumed to be between -2 and +2 (95%) in the normal population according to Kubios software, and the grouping method was based on this situation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The evaluations were carried out by the second researcher
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 18 and 40 years old.
- •No previous vagus nerve stimulation
排除标准
- •Using of any drug, alcohol or smoking.
- •Pregnancy.
- •Known history of acute or chronic illness.
- •Being in the post or peri-menopausal stage.
结局指标
主要结局
Systolic Blood Pressure
时间窗: Up to 6 Months
The systolic blood pressure of the participants was measured with an electronic blood pressure monitor.
Diastolic Blood Pressure
时间窗: Up to 6 Months
The diastolic blood pressure of the participants was measured with an electronic blood pressure monitor.
Pulse Rate
时间窗: Up to 6 Months
The pulse rate of the participants was measured with an electronic blood pressure monitor.
次要结局
未报告次要终点
研究者
Alper Percin
Principal Investigator
Bahçeşehir University