NCT01082393已完成4 期
Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis)
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- percentage of skin pigmentation in the treated area
研究概览
简要总结
We will investigate the process of vitiligo induction and the influence of different commonly used cream treatments on this process. Studies comparing different treatments for vitiligo in the induction stage of the disease are still missing. The study hypothesis = cream treatment can stop actively spreading vitiligo lesions during the early induction stage of the disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female,
- •Age 18-70 years,
- •Extensive vitiligo (> 50% body surface area),
- •Patients asking for depigmenting therapy,
- •Not pregnant.
排除标准
- •Children,
- •Non extensive vitiligo (< 50% boy surface area),
- •Patients not asking for depigmenting therapies,
- •Pregnant.
研究组 & 干预措施
topical tacrolimus
Active Comparator
干预措施: topical tacrolimus treatment (Drug)
topical pimecrolimus
Active Comparator
干预措施: topical pimecrolimus treatment (Drug)
local steroids
Active Comparator
干预措施: local mometasone furoate treatment (Drug)
cold cream
Placebo Comparator
干预措施: cold cream (Drug)
结局指标
主要结局
percentage of skin pigmentation in the treated area
时间窗: after 1 day, 10 days, 30 days and 60 days
digital image analysis system for surface measurement
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
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