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临床试验/NCT05739838
NCT05739838进行中(未招募)不适用

Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients. Clinical and Biochemical Study

Faculty of Dental Medicine for Girls2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
20
试验地点
2
主要终点
Rate of orthodontic tooth movement

研究概览

简要总结

To investigate the effect of Low Level Laser therapy on orthodontic tooth movement of periodontally compromised patients by evaluating the rate of orthodontic tooth movement and the level of Osteocalcin in the gingival crevicular fluid.

详细描述

Low-Level laser therapy has been reported as an effective adjunct to non surgical periodontal treatment for inflammation control and tissue reparation in patients with periodontitis. Previous studies have shown that application of low-level laser therapy reduced pocket depth and decreased the inflammatory process through regulatory control of inflammatory cytokines level, therefore this study will investigate the effect of low-level laser on the periodontal tissue .Accelerating orthodontic tooth movement is one of the primary demand in orthodontics to prevent side effects as root resorption, caries and decreased patient compliance . Numerous researchers have also studied the use of LLLT in accelerating orthodontic tooth movement and have considered the laser to be effective while others achieved the opposite . Hence, This study is aiming to investigate the effects of LLLT in accelerating tooth movement.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
25 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • No systemic disease.
  • No history medication (antibiotics and/or anti inflammatory) in the previous 4 months.
  • Self motivated patients with acceptable oral hygien.

排除标准

  • Previous orthodontic treatment
  • Aggressive periodontitis
  • pregnant patients

结局指标

主要结局

Rate of orthodontic tooth movement

时间窗: 6 months

Rate of mandibular canine retraction

次要结局

  • Osteocalcin level in GCF(6 months)

研究者

发起方
Faculty of Dental Medicine for Girls
申办方类型
Other Gov
责任方
Sponsor

研究点 (2)

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