Influence of Caffeine and Green Tea Extracts Consumption on Basal, Peri- and Post-exercise Fat Oxidation
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Fat oxidation as measured by indirect calorimetry
研究概览
简要总结
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
详细描述
This study investigates whether consuming an energy drink containing caffeine and green tea extract before exercise increases fat burning (oxidation) compared with a placebo drink. Healthy, moderately active adults will attend three visits at clinic over 3-5 weeks. The first visit determines each participant's individual exercise intensity that maximises fat use during cycling. At two subsequent visits, participants will consume either the active drink or a placebo before completing a 30-minute cycling session at their personalised intensity. Fat and carbohydrate use, heart rate, blood pressure, and subjective responses will be measured at rest, during exercise, and after exercise using a double-blind, crossover design.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Passing the Exercise and Sport Science Australia adult pre-exercise screening system (APSS) stage 1 & 2 (see appendix 4).
- •Between the ages of 18 and 45,
- •Not sedentary, and not completing more than 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
- •Ability to commit to in principle fulfilment of all 3 trial visits,
- •No history of coagulopathy e.g., DVT, stroke,
- •No known heart disease,
- •No known pancreatic insufficiency,
- •No known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
- •BMI of 22.0 to 34.9 kg/m2,
- •No known allergies to caffeine or green tea extract,
- •No known type I or II diabetes,
- •No uncontrolled concurrent illness,
- •No known current pregnancy or breastfeeding women
- •No current regular consumption of supplements (>2 times a week) or foods and drinks containing caffeine and/or green tea extracts (>2 times per day, weekly).
- •Agree not to consume caffeine for 12-hours prior to the clinic visit.
排除标准
- •Triggering any of the exclusion screening criteria as outlined below, and in compliment with the Exercise and Sport Science Australia adult pre-exercise screening system (APSS).
- •Under the age of 18 or over the age of 45,
- •Sedentary, or completing over 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
- •Inability to commit to in principle fulfilment of all 3 trial visits,
- •History of coagulopathy e.g., DVT, stroke,
- •Known heart disease,
- •Known pancreatic insufficiency,
- •Known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
- •BMI < 22.0 or > 34.9 kg/m2,
- •Known allergies to caffeine or green tea extract,
- •Known type I or II diabetes,
- •Uncontrolled concurrent illness,
- •Taking GLP-1 agonists, caffeine, or any other medication known to affect metabolism.
- •Known current pregnancy or breastfeeding women.
- •Currently regularly consuming supplements, foods or drinks containing a caffeine and green tea extract blend, or not willing to abstain for the study
研究组 & 干预措施
Active
Two 355 mL cans of "XS Energy + BURN" drink containing caffeine and green tea extract.
干预措施: Active (Green tea and caffeine) (Dietary Supplement)
Placebo
Two 355 mL cans of placebo drink but without the active ingredients (caffeine and green tea extract).
干预措施: Placebo (Other)
结局指标
主要结局
Fat oxidation as measured by indirect calorimetry
时间窗: Baseline to 30 mins post exercise
Change from baseline to the end of the study period in Fat oxidation as measured by indirect calorimetry (metabolic cart); baseline (pre-drink), post-drink (pre-exercise), time sequence e.g., every 5-min during exercise, 10, 20 and 30-min post-exercise. Change from baseline \& total. Fat oxidation will be measured continuously throughout the exercise and the 30-min post-exercise window, to facilitate total, and any other temporal fat oxidation timepoints.
次要结局
- Carbohydrate oxidation; indirect calorimetry(Baseline to 30 mins post exercise)
- Respiratory exchange ratio; indirect calorimetry(Baseline to 30 mins post exercise)
- Exercise efficiency; indirect calorimetry(Baseline to 30 mins post exercise)