JPRN-UMIN000000558已完成1 期
Study on diagnosis of Alzheimer disease by amyloid imaging: A multi-center trial - A PET study of amyloid imaging in Alzheimer disease
Study Group on diagnosis of Alzheimer disease by amyloid imaging using [11C]BF-2270 个研究点目标入组 80 人开始时间: 2007年1月10日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
Initial PET studies using [11C]BF-227 have been started at Tohoku University and Tokyo Metropolitan Institute of Gerontology. The accumulation patterns of [11C]BF-227 in Alzheimer patients were different from those of normal volunteers. Increased brain areas were consistent with those rich with amyloid plaques. The half of MCI patients showed increased accumulation of [11C]BF227. We also compared PET amyloid imaging to FDG-PET, and the preliminary results suggested the superiority of amyloid imaging.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1)The past and present history of alcoholism. 2)The past and present history of epilepsy 3)Education period is less than 6 years. 4)There are no persons who can give any information on patients symptoms. 5)Diabetic patients treated with insulin 6)Patients treated with antidepressants, antipsychotics, and long-term sedative-hypnotics. 7)Severe complication including malignancy, heart failure, hepatic dysfunction, renal dysfunction, endocrine disorders, etc. 8)Other patients and volunteers that investigators and medical doctors need to exclude.
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