NCT03369925已完成不适用
A Parallel, Double-Blind Study to Assess the Cognitive Effects of a Citicoline Supplement (Cognizin®) in Men and Women With Age-Associated Memory Impairment
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Standardized scores on the Cambridge Brain Sciences that measure cognitive assessment
研究概览
简要总结
The objective of this trial is to determine the effects of citicoline on cognitive performance in healthy Men and Women with Age-Associated Memory Impairment compared to a placebo.
详细描述
This study is a 12-week, randomized, double-blind, placebo-controlled trial of citicoline in healthy men and women with Age-Associated Memory Impairment. Cognitive assessments will be performed to determine whether citicoline administration with supportive memory, compared to placebo administration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •male or female, 50-85 years of age
- •at least a high school diploma or the equivalent
- •self-reported memory loss
- •scores ≥24 on the Mini-Mental State Examination, ≥85 on the Kaufman Brief Intelligence Test, Second Edition, ≤5 on the Geriatric Depression Scale, and 4, 3, or 2 on the Spatial Span Test
- •no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results
排除标准
- •color blind
- •abnormal laboratory test results
- •major medical or neurological illness
- •female who is pregnant, planning to be pregnant during the study period
- •requiring treatment with a drug which might obscure the action of the study treatment
研究组 & 干预措施
Cognizin
Experimental
干预措施: Citicoline supplement (Dietary Supplement)
Placebo
Placebo Comparator
干预措施: Placebo supplement (Dietary Supplement)
结局指标
主要结局
Standardized scores on the Cambridge Brain Sciences that measure cognitive assessment
时间窗: 12 weeks
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Cognitive Effects of Citicoline on Attention in Healthy Mean and WomenNCT04967157Kirin Holdings Company, Limited148
招募中
不适用
A Clinical Study on the Efficacy of Cognitive Distraction Focus Relaxation Therapy Based on MRPainNCT06290011Xinhua Hospital, Shanghai Jiao Tong University School of Medicine132
已完成
不适用
Intervention Utilizing a Computerized Cognitive Rehabilitation Program (D-kit/EF1)Mild Intellectual DisabilityBorderline Intellectual FunctioningNCT05933005University of California, San Francisco11
已完成
4 期
A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic TherapyParkinson's DiseaseNCT01497652Georgetown University34
已完成
2 期
Safety and Cognitive Function Study of EVP-6124 in Patients With SchizophreniaCentral Nervous System DiseasesCognitionSchizophreniaNCT00968851FORUM Pharmaceuticals Inc317