High-resolution Imaging of Corneal Lesions With Optical Coherence Tomography (OCT) - A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4
- 试验地点
- 2
- 主要终点
- Imaging of corneal abrasions and infiltrates
研究概览
简要总结
Corneal lesions such as corneal abrasions and corneal infiltrates are common in clinical practice. The current study seeks to investigate whether high-resolution OCT is suitable for imaging of these corneal lesions. The present study has the character of a pilot study and the results are intended to be used to develop a standardized protocol for imaging and analysis of these corneal lesions. Based on this protocol, further studies investigating the pathophysiology of corneal lesions or evaluating therapeutic success can be planned.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women aged over 18 years
- •Newly diagnosed corneal abrasion or corneal infiltrate
排除标准
- •Recurrent corneal erosion
- •Participation in a clinical trial in the previous 3 weeks
- •Presence of any abnormalities preventing reliable measurements as judged by the investigator
- •Any contraindication for topical application of Novain 0.4% eye drops for topical anesthesia or of Minims-Fluorescein Sodium eye drops for fluorescein staining
- •Pregnancy, planned pregnancy or lactating
结局指标
主要结局
Imaging of corneal abrasions and infiltrates
时间窗: 1 day
The aim of this pilot study is to investigate whether imaging of these corneal alterations is possible.
次要结局
- Size and depth of corneal lesions as assessed with high-resolution OCT(1 day)
- Slit lamp biomicroscopy with fluorescein staining(1 day)
研究者
Gerhard Garhofer
Assoc. Prof. PD Dr.
Medical University of Vienna