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临床试验/CTRI/2025/07/091890
CTRI/2025/07/091890尚未招募3 期

Evaluation Of Effect Of Syzygium Cumini & Orange Peel Mouthwash On Periodontal Health In Patients Undergoing Orthodontic Treatment- A Randomized Controlled Trial.

self1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年12月24日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
plaue index, gingival index

研究概览

简要总结

Orthodontic treatment plays a crucial role in aligning teeth and improving both function and aesthetics. However, it can also pose challenges to periodontal health. Common periodontal complications associated with orthodontic therapy include gingivitis, periodontitis, gingival recession or hypertrophy, alveolar bone loss, dehiscence, fenestration, interdental folds, and the formation of dark triangles. The primary factor contributing to these issues is plaque accumulation, which plays a key role in the initiation, progression, and recurrence of periodontal disease, particularly in patients with a compromised periodontium. The presence of orthodontic brackets and elastics can hinder effective plaque removal, increasing the risk of gingivitis. Additionally, orthodontic treatment alters the balance of oral microflora by promoting bacterial retention, further exacerbating periodontal concerns.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
35.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • undergoing orthodontic treatment and having PPD and CAL of more than 4 mm.

排除标准

  • Patients who have undergone any periodontal therapy in the past 6 months.
  • Patients with systemic diseases.
  • History of any medication including antibiotic treatment within the previous 3 months or regular use of specific drugs known to affect periodontal tissues.
  • Pregnant women and lactating mothers.

结局指标

主要结局

plaue index, gingival index

时间窗: BASELINE, 1 MONTH, 3 MONTHS

次要结局

  • PBI,PPD,CAL(BASELINE,1 MONTH, 3 MONTHS)

研究者

发起方
self
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

DR SUREKHA RATHOD

Rnajeet Deshmukh Dental College, Nagpur

研究点 (1)

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