NCT00768807已完成不适用
Structural and Functional Left Ventricular Remodelling in Patients With Obstructive Sleep Apnea
Associação Fundo de Incentivo à Pesquisa2 个研究点 分布在 1 个国家目标入组 450 人开始时间: 2009年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 450
- 试验地点
- 2
- 主要终点
- Improvement of left ventricular diastolic echo variable
研究概览
简要总结
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left ventricular function and structure after 06 months of continuous positive airway pressure treatment.
详细描述
Several studies have been suggesting that Obstructive Sleep Apnea contributes to deterioration of left ventricular diastolic function. It may be associated to increased risk of cardiovascular events. We hypothesized that morphological and functional left ventricular changes might be reverted after treatment with Continuous positive airway pressure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 35 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apnea-hypopnea index higher than 5 events per hour
排除标准
- •Body mass index higher than 40 kg/m2
结局指标
主要结局
Improvement of left ventricular diastolic echo variable
时间窗: 06 months
次要结局
未报告次要终点
研究者
Wercules Antonio Alves de Oliveira
Dr.
Associação Fundo de Incentivo à Pesquisa
研究点 (2)
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