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临床试验/NCT04975503
NCT04975503已完成不适用

Classical Risk Factors in Young Middle Eastern Women With Atherosclerotic Cardiovascular Disease

Jordan Collaborating Cardiology Group1 个研究点 分布在 1 个国家目标入组 627 人开始时间: 2021年8月22日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
627
试验地点
1
主要终点
Prevalence of classical CVD risk factors

研究概览

简要总结

Cardiovascular disease continues to be the leading cause of death among women in the Middle East, including Jordan. Sex-specific data focused on cardiovascular disease have been increasing steadily, yet is not the subgroup of young women. This study focuses on classical and novel risk factors of cardiovascular disease in young women compared with older women.

详细描述

This is the introduction of a new study at Istishari entitled: "The Classical Risk Factors in Young Middle Eastern Women with Atherosclerotic Cardiovascular Disease" This is an investigator-initiated, cross-sectional, non-interventional, observational study.

Medical research in Jordan is a basic responsibility of all medical sectors in the country. Despite the drastic growth and advances of medical services, the volume of the local medical research is, at best estimate, scarce. The emerging role of private medical groups, private hospitals, and residency programs in cooperation with other medical sectors and medical schools, in conducting, presenting, and publishing such studies should be encouraged and supported. A major indicator of judging the credibility and quality of any medical research project is to look at the conferences the research was presented at and the journals it was published in.

This is the 10th major project of the Jordan Collaborating Cardiology Group (JCC) and the first in cooperation with the Istishari Hospital Internal Medicine Residency Program (see Appendix 1. Timeline of JCC Group studies) The first project was JoHARTS that evaluated coronary risk factors and dyslipidemia in 5000 individuals with ACS, stable CAD, and non CAD patients. The 2nd project was CAPRIS evaluated the prognostic implications of hs-CRP in ACS from admission to 1 year. The 3rd project was MINTOR that evaluated onset, triggers, reperfusion strategies, and hospital mortality in more than 950 Jordanians with acute ST-elevation MI. The 4th project was GLORY study that evaluated the prevalence of glucometabolic states among ACS patients, prognosis up to 1 year, and TIMI risk score . The 5th was JoPCR1 that evaluated outcome post PCI in 2426 ACS and non ACS patients in 12 tertiary care centers for the incidence of death, stent thrombosis, revascularization, bleeding, impact of gender, DM, renal dysfunction, and age on outcome, GRACE, and CRUSADE risk scores. The 6th is the colchicine study of AF prevention in open heart surgery, one is completed with 1 mg dose and one is ongoing with reduced dose. The 7th and 8th projects are ongoing and study statin eligibility in patients admitted with MI (Statin EPIC) and decade or more survivors after coronary revascularization. The 8th was the Jordanian AF study which evaluated patients with AF in ambulatory and out-patient settings. The 9th was the JoCORE study that evaluated acute CV events due to the stresses of the covid-19 pandemic.

One population subgroup is under studied in the world literature as well as the local literature. The young women who have documented CVD. This group represents only a small proportion of the CVD population in all countries.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Women aged 18 y or more.
  • Documented CVD (CAD stable or ACS, PCI, CABG, CVA/TIA, carotid disease, PAD).

排除标准

  • Women younger than 18 years of age.
  • No documented CVD.

结局指标

主要结局

Prevalence of classical CVD risk factors

时间窗: August 2021 to September 2020.

To study the prevalence of the 4 classical risk factors (HTN, DM, smoking, and dyslipidemia) in young women (younger than 50 years of age) who have documented CVD in ambulatory and in-patient settings and compare the data with women older than 50 y of age with CVD.

次要结局

  • Prevalence of novel/emerging CVD risk factors(August 2021 to September 2022.)

研究者

发起方
Jordan Collaborating Cardiology Group
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayman J Hammoudeh, MD, FACC

Interventional Cardiologist, Department of cardiology, Istishari Hospital, Amman, Jordan

Jordan Collaborating Cardiology Group

研究点 (1)

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