NL-OMON40818已完成2 期
The effects of BCG-vaccination on the immune response induced by influenza-vaccination in healthy volunteers. A pilot proof-of-principle study. - Effects of BCG on influenza-induced immune response
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 72 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Age >=18 and <=35 yrs or >=65 yrs
排除标准
- •- Prior exposure to *Influvac* influenza virus strains , measured by antibody titres. Previous exposure is defined by antibody titres >=1:40.
- •- History of influenza vaccination within the year prior to study entry
- •- History of BCG vaccination within 5 years prior to study entry
- •- History of Mantoux testing within the year prior to study entry
- •- Vaccination other than BCG or influenza, within 3 months prior to study or within study period
- •- Medical history of any disease associated with immune deficiency
- •- Clinically significant acute illness, including infections, within 4 weeks before vaccination
- •- Participation in a drug trial or donation of blood 3 months prior to study entry
- •- Use of recreational drugs within 21 days prior to experiment day
- •- Recent hospital admission or surgery with general anaesthesia (<3 months)
- •- Known chronic kidney or liver disease
- •- Latent or active tuberculosis infection
研究者
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