Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,153
- 试验地点
- 2
- 主要终点
- Measure the mean thickness of postganglionic fibers
研究概览
简要总结
The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.
The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persons who have given their written consent
- •Persons who are taking part in the Dijon 3C study
排除标准
- •Persons who are not registered with social security agency
- •Persons who are unable to sit upright during a consultation
结局指标
主要结局
Measure the mean thickness of postganglionic fibers
时间窗: T=7 years of the 3C cohort
Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.
次要结局
未报告次要终点