Evaluation of Marginal Bone Loss After Immediate Implant Placement in Maxillary Esthetic Zone With Nanobone Versus Xenograft (Randomized Clinical Trial)
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Measurement of Crestal Bone Loss in grafted socket
研究概览
简要总结
Immediate implant placement has a success rate from 94-100 % . After tooth extraction there is a loss in the horizontal and vertical dimension by about 3-6 mm and 1-2 mm respectively and alveolar crest resorption of about 44% especially through 6 months after extraction.
After immediate implant placement there is usually a void between the implant and the socket walls which is called jumping distance or gap which may heal spontaneously or need bone graft to bridge the space. If the gap is 1-2 mm it may heal spontaneously more than that this will need bone graft. There is no evidence that the graft impairs osseointegration Development of artificial bone has increasingly progressed in the last few years. Nanobone "nanocrystalline hydroxyapatite embedded in a porous silica gel matrix bone graft is introduced which has osseoconductive and biomimetic properties .the sub-micron modification in the bone substitute will enhance osteogenic property. It bind to the bone by stimulation of osteoblast activity and enhance growth factors which improve bone healing and provide more strength and stability to the implant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients with badly broken teeth in upper esthetic zone indicated for extraction, presence of at least 4 mm of bone beyond the root apex to guarantee implant primary stability, implant placement within the alveoli confines.
- •Both sexes.
- •No intraoral soft and hard tissue pathology.
- •No systemic condition that contraindicate implant placement.
排除标准
- •Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
- •Heavy smokers more than 20 cigarettes per day .(24)
- •Patients with systemic disease that may affect normal healing.
- •Psychiatric problems
- •Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site
结局指标
主要结局
Measurement of Crestal Bone Loss in grafted socket
时间窗: 3 months after implant placement
次要结局
未报告次要终点
研究者
Abdullah Mohammed Farahat
Principal Investigator
Cairo University
