ACTRN12618001450202已完成未知
The Ketogenic Diet In Alzheimer's: A Randomized Crossover Trial
Waikato Hospital Neurology Department0 个研究点目标入组 26 人开始时间: 2018年8月28日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 50 Years 至 90 Years（—）
- 性别
- All
入选标准
- •(1) Aged 50 to 90 years.
- •(2) Satisfies revised NINCDS-ADRDA criteria for probable AD.
- •(3) Mild dementia (DSRS <19) and sufficient consent capacity (passing grade on a modified AD Informed Consent questionnaire, defined as at least 70% of questions 1 to 10 correct and 100% of questions 11 to 14 correct on the first or second administration, with the word medication” replaced with diet”).
- •(3) BMI >18.5.
- •(4) An active study partner able and willing to follow either diet plan.
排除标准
- •(1)Inability to speak or understand English.
- •(2)Moderate or severe depression (short form Geriatric Depression score >8).
- •(3)Substantial concomitant cerebrovascular disease (Hachinski Ischemia score >4).
- •(4)Any change in dosage of an acetylcholinesterase inhibitor or memantine within 6 weeks before commencing the diets.
- •(5)A concurrent medical or psychiatric condition that in the opinion of the investigators would make it difficult to complete the study.
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