NCT02559401已完成不适用
Validation of Edema-invariant Multi-shell High Angular Resolution Diffusion Imaging (msHARDI)-Based Tractography With Intra-operative Cortical Stimulation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Number of subjects providing completion of the neurocognitive battery
研究概览
简要总结
Currently, standard-of-care tractography is based on information obtained from diffusion tensor imaging (DTI). DTI is a diffusion magnetic resonance imaging (dMRI) technique that is routinely obtained on neurosurgical patients to assist in pre-operative planning. The primary objective of the proposed study is to determine the ability of msHARDI-based tractography to discern fibers in edematous brain regions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •brain lesions, including but not limited to tumors, epileptic foci, and vascular abnormalities, in or around eloquent brain regions (i.e., motor, language);
- •clinical need for pre-operative 'advanced imaging' (which includes conventional DTI);
- •age between 18-80 years of age;
- •male or female gender. Eloquent regions include: Temporal and frontal lobes (speech/language); bilateral occipital lobes (vision); bilateral parietal lobes (sensation); and bilateral motor cortex (movement).
排除标准
- •a contraindication for obtaining an MRI scan (e.g. implanted devices, retrained foreign body)
- •pregnancy
- •absence of the capacity to make medical decisions or provide informed consent.
结局指标
主要结局
Number of subjects providing completion of the neurocognitive battery
时间窗: 2 years
次要结局
未报告次要终点
研究者
研究点 (1)
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