Comparison of ascending aortic strain between hypertensives and healthy controls
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 189
- 试验地点
- 1
- 主要终点
- Aortic strain
研究概览
简要总结
The study titled Comparison of ascending aortic strain between hypertensives and healthy controls using echocardiographic imaging is a single-center prospective observational study. The study aims to compare ascending aortic strain between hypertensive patients and healthy controls. The primary objective is to compare ascending aortic strain between hypertensive patients and healthy controls. The secondary objective is to examine the correlation between aortic strain and LV mass in hypertensive patients and to find the correlation between aortic strain and LV function parameters.
Patients diagnosed with hypertension according to the 2025 AHA/ACC guidelines and healthy controls referred for an echocardiography will be screened based on inclusion and exclusion criteria. Healthy controls will include individuals who come for routine cardiac evaluation with no comorbidities. Study will be explained to the participants, and informed consent will be obtained. Demographic data will be documented from the case sheet. Echocardiographic parameters will be recorded and stored along with connected ECG. Initially, a few cases will be evaluated for inter-rater reliability between two investigators (a postgraduate student and an experienced sonographer) for echocardiographic parameters such as aortic strain, LV strain, LV mass, etc.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Case group: Age-30 to 50 years, either gender, known case of hypertension with or without medication Control group: Age-30 to 50 years, either gender.
排除标准
- •Coronary artery disease,
- •Congenital heart disease,
- •Cardiomyopathy,
- •Cerebrovascular disease,
- •Chronic kidney disease,
- •Significant (more than mild) primary valvular disease,
- •Poor echocardiographic window.
结局指标
主要结局
Aortic strain
时间窗: Baseline
LV mass
时间窗: Baseline
LV function
时间窗: Baseline
次要结局
未报告次要终点
研究者
Poojary Manasi Bhoja
Manipal College of Health Professions
