Prioritising and optimising multiple medications in elderly multi-morbid patients in general practice: a pragmatic cluster-randomised controlled trial

Johann Wolfgang Goethe University (Germany)0 个研究点目标入组 502 人开始时间: 2010年8月31日最近更新: 2019年10月14日

试验速览

•1. At least 60 years old of both sexes
•2. At least three chronic diseases affecting two or more organ systems, which require pharmaceutical treatment
•3. At least five long-term prescriptions with systemic effects
•4. Health care provided by GP (at least one contact in most recent quarter)
•5. Patient is legally competent to sign any documents
•6. Ability to understand and participate in trial of own free will, to fill out questionnaires and participate in telephone interviews
•7. Written informed consent to participate in trial
•1. Practice serves members of the German statutory health insurance system
•2. GP practice
•3. Physician is specialised in general practice or internal medicine, or doctor with no specialist field
•4. Internet access
•5. Investigator's agreement to fulfil the contractual obligations arising from the trial
•6. Investigator's agreement to the training of a health care assistant (HCA) from the practice for the intervention, as required by the trial

•1. Diseases cause life expectancy of less than 12 months
•2. Abuse of alcohol or illegal drugs and visible clinical signs or symptoms thereof
•3. Cognitive impairment that prevents trial participation (mini-mental state examination [MMSE] less than 26)
•4. Emotional stress that prevents trial participation
•5. Participation in a clinical trial within the last 30 days
•1. Practice focuses on unconventional medical treatments
•2. Practice focuses on special indications (e.g. human immunodeficiency virus [HIV])

发起方

Johann Wolfgang Goethe University (Germany)