Cerebral Microembolism in Interventional Cardiology Procedures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Quality of cerebral microemboli (solid vs. gaseous)
研究概览
简要总结
During different interventional cardiology procedures we aim to identify cerebral microemboli load. Further we aim to differentiate the quality and the quantity of cerebral microemboli.We will measure cerebral microemboli in different interventional phases, e.g. during valve deployment, rapid pacing, post-implantation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Interventional cardiology procedure (TAVI, MitraClip, TricuspidalClip)
排除标准
- •Allergy to ultrasound gel or materials contained in the TCD probe
- •Missing temporal bone window
结局指标
主要结局
Quality of cerebral microemboli (solid vs. gaseous)
时间窗: intraoperative phase, expected to be approx. 4 hours
The quality of cerebral microemboli is measured by Doppler ultrasonography which automatically detects and analyses the Doppler signal coming from the middle cerebral artery. According to the strength of signal reflection, the signal will be qualified as solid or gaseous.
次要结局
- Quantity of cerebral microemboli load(intraoperative phase, expected to be approx. 4 hours)
- Cerebral hemispheric differences (left vs. right)(intraoperative phase, expected to be approx. 4 hours)
研究者
Gabor Erdös
Principal Investigator
Insel Gruppe AG, University Hospital Bern