NL-OMON32767撤回不适用
Consequences of suboptimal glucocorticoid replacement therapy in Addison*s disease; The metabolic syndrome and quality of life. - Consequences of suboptimal GRTin Addison*s disease
niversitair Medisch Centrum Utrecht0 个研究点目标入组 242 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 242
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- primary adrenal insufficiency
- •- 18-70 years
- •- stable glucocorticoid replacement therapy (no adjustments of regime and dosage for 3 months)
排除标准
- •- intercurrent infectious or serious disease for which it is necessary to increase
- •glucocorticoid dosage
- •- high dose inhalation glucocorticoids (>800 microgram a day)
- •- pregnancy
研究者
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Consequences of suboptimal glucocorticoid replacement therapy in Addison’s disease; The metabolic syndrome and QoL.Addison's disease, metabolic syndrome, quality of life, glucocorticoid receptor polymorphismsNL-OMON22793niversity Medical Center Utrecht120
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Optimal glucocorticoid replacement therapy in adrenocorticotropin (ACTH) deficient hypopituitary patients - Optimal glucocorticoid replacement10 male patients with hypopituitarism resulting in ACTH (adrenocorticotropin) deficiency (ICD E23.0) will be studied on varying doses of hydrocortisone replacement therapy. THis is not a new medication for these patients.10 healthy male volunteers will be studied as control subjects. They will NOT receive hydrocortisone.MedDRA version: 9.1Level: LLTClassification code 10021067Term: HypopituitarismMedDRA version: 9.1Level: LLTClassification code 10033662Term: PanhypopituitarismMedDRA version: 9.1Level: LLTClassification code 10057217Term: Isolated ACTH deficiencyEUCTR2007-005018-37-IEAmar Agha20