The Effect of Intravenous Tranexamic Acid in Percutaneous Renal Biopsy: A Single Center, Triple-blinded, Randomized Controlled Trial - TRANExamic acid in renal bioPSY study (TRANEPSY study)

We assessed 90 adult patients for study eligibility, of whom, 56 were randomly allocated into the three groups: 20 for high-dose tranexamic acid, 19 for low-dose tranexamic acid, and 17 for placebo. The median size of perirenal hematoma was 200 mm2 [interquartile range 21-650] in the high-dose tranexamic acid group, 52 mm2 [0-139] in the low-dose tranexamic acid group, and 0 mm2 [0-339] in the placebo group (p = 0.048 for high-dose tranexamic acid vs. placebo).