DRKS00033843招募中不适用
Clinical exploratory study on the relationship between recurrent aphthous stomatitis and the oral microbiota, nutrient balance and other health parameters. - Aphthae study
IVERSITÄTSKLINIKUM FREIBURG Department f. Zahn-, Mund- u. Kieferheilkunde Klinik für Zahnerhaltungskunde und Parodontologie0 个研究点目标入组 40 人开始时间: 2024年3月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 65 Years(—)
- 性别
- All
入选标准
- •Aphthous cohort: recurrent aphthae
- •- Healthy cohort: no occurrence of aphthae to date
- •- Non-smoker
- •- Last tooth brushing at least 12 hours ago
- •- Fasting for blood collection (8 to 12 hours without eating or drinking
- •nothing to drink (except water))
排除标准
- •- Pregnancy
- •- Breastfeeding
- •- Serious general illness (diabetes mellitus, oncological diseases,
- •immunosuppression oncological diseases, immunosuppression, e.g. due
- •to HIV infection, blood diseases)
- •- chronic immunological diseases (e.g. Crohn's disease, coeliac disease,
- •lichen planus)
- •- rheumatic diseases (e.g. Behçet's syndrome)
- •- Periodontitis and chronic oral mucosal diseases
- •- Use of antibiotics/immunosuppressants within the last 6 months
- •- Use of mouth rinses in the last 4 weeks
- •- Use of toothbrushes for the tongue in the last 4 weeks
- •- Treatment of acute aphthae with medication/home remedies (e.g.
- •Tea tree oil, rhubarb extract, cortisone, analgesic gels)
研究者
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