Pain Reduction by Inducing Sensory-Motor Adaptation in Complex Regional Pain Syndrome (CRPS): a double-blind randomized control trial

niversity of Bath0 个研究点目标入组 76 人开始时间: 2017年3月27日最近更新: 2021年11月1日

试验速览

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32075590 protocol (added 24/02/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/32833791/ results (added 27/08/2020)

•Healthy volunteers:
•1. Willing and able to give informed consent for participation in the study
•2. Aged 18-80
•3. Healthy and without current pain
•1. Willing and able to give informed consent for participation in the study
•2. Aged 18-80
•3. Diagnosed with CRPS type I of minimum three months chronicity, primarily affecting one upper limb, based on Budapest research criteria that will be assessed on the first research visit
•4. Reporting current pain intensity =2 on a 0-10 Numeric Rating Scale on the first and second research visit (as of 05/10/2018)

•All participants:
•1. A history of neurological disorder (e.g. a stroke, neurodegenerative disease, traumatic brain injury)
•2. Classified as legally blind
•3. Lacking sufficient English language ability to provide informed consent
•1. CRPS affecting both sides of the body, or confirmed presence of nerve damage
•2. Dystonia or any other physical limitation that is severe enough to prevent movement of the affected limb
•Decisions whether or not to exclude a participant suffering from a psychiatric disorder will be made on a case-by-case basis, as patients with CRPS often present with co-morbid depression and anxiety.

发起方

niversity of Bath