The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 175
- 试验地点
- 1
- 主要终点
- To evaluate the development of AR in children who were previously diagnosed with NAR
研究概览
简要总结
The purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
详细描述
Rhinitis is a common condition associated with significant effects on quality of life. Rhinitis may be divided into two groups, those with concurrent allergy (allergic rhinitis, AR) and those without allergy but who still suffer from nasal symptoms (nonallergic rhinitis, NAR).
Evidence indicated that adult with NAR can have de novo sensitization to aeroallergen (24%), suggesting that patients with NAR might evolve to AR. Thus the purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 1 Year 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children between the age of 1 year and 15 years with the diagnosis of nonallergic rhinitis who are attending the pediatric allergy clinic during Jan 2005 - Dec 2007.
排除标准
- •Patients who have allergic rhinitis and underlying disease eg.chronic renal disease, liver disease, heart disease, cancer.
结局指标
主要结局
To evaluate the development of AR in children who were previously diagnosed with NAR
时间窗: 24 months
次要结局
- To determine the persistence and severity of the symptoms, new comorbidities and triggering factors in children with nonallergic rhinitis(24 months)
研究者
Orathai Piboonpocanun
Department of Pediatrics, Faculty of medicine, Siriraj hospital
Mahidol University