Investigating the feasibility and tolerability of home-based, remotely-supervised transcranial direct current stimulation (tDCS) during attention training in children with acquired brain injury

Professor Karen Barlow0 个研究点目标入组 30 人开始时间: 2022年12月19日最近更新: 2023年4月10日

适应症

试验速览

暂无简介。

•Aged between 7 and 18 years (inclusive)
•Acquired brain injury (including mild to severe TBI)
•English language skills sufficient to comprehend study information and complete assessments (self-report)
•At least 3 months post injury (for mild TBI)
•At least one year post-injury (for moderate – severe TBI)
•Access to internet at home
•TBI injury severity
•Mild: Received a Glasgow coma scale (GCS) score of between 13 and 15 upon ED evaluation (if available); experienced <24 h post-traumatic amnesia (PTA)
•Moderate: Loss of consciousness between 30 min and 24 h; GCS between 9 and 12; PTA between 24 h and 7 days]
•Severe: GCS<9; PTA for more than 7 days]

•Contra-indications to tDCS e.g.
•- Metal implants
•- Serious or unstable illness or medical condition
•- Current or suspected pregnancy or current lactation
•- Skull defects underneath stimulation sites
•- Scalp wound/skin problem preventing placement of EEG and stimulation leads
•- Epilepsy or other seizure disorders
•Acquired brain injury due to hypoxic-ischemic encephalopathy
•Significant past medical or psychiatric history before injury
•Profound memory impairments according to medical history
•Recent or planned change in neuroactive drugs (i.e., changed within 3 weeks of tDCS; e.g., anticonvulsants, benzodiazepines, GABA antagonists, etc.).
•Pre-existing neurological disorder, including moderate to severe learning difficulties
•Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.

发起方

Professor Karen Barlow