If Adrenal Incidentalomas Have the Influences to Occur and Progress in Patients With Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- Incidence rate of Adrenal incidentalomas
研究概览
简要总结
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke. Stroke is a diseases which could cause of disability and death worldwide. In clinical practice, detailed information about the association between stroke and AIs is not available. In this study, the investigators aimed to investigate the risk for disability and death in the large group of stroke patients with AIs.
详细描述
Background:
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke . The investigators aimed to investigate the risk for disability and death in the large group of stroke patients with AIs.
Objective:
To measure the association between stroke and levels of autonomous cortisol secretion in patients with AIs.
Design:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •stroke disease , such as Cerebral infarction、Intracerebral hemorrhage and Subarachnoid hemorrhage.
排除标准
- •presence of metastatic cancer;
- •AIs smaller than 1 cm;
- •nonadenoma lesions, such as myelolipomas,hemorrhages, and cysts;
- •oral glucocorticoid treatment with more than single doses in the past 3 months;
- •use of inhaled steroids or medication affecting dexamethasone metabolism;
- •systemic estrogen treatment.
结局指标
主要结局
Incidence rate of Adrenal incidentalomas
时间窗: 5 years
Assess the standardised incidence rate of AIs in all patients with stroke
Plasma cortisol level
时间窗: 5 years
Plasma cortisol level after a 1-mg dexamethasone suppression test
次要结局
- Diameter of Adrenal incidentalomas(5 years)