NCT00654459已完成不适用
Effects of Armolipid Plus on Cholesterol Levels and Endothelial Function
Federico II University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2007年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The primary outcome measure of this study was the percentage change from baseline of total cholesterol (C), LDL- cholesterol (LDL-C), HDL-cholesterol (HDL-C),and Triglycerides (Tg) plasma concentrations.
研究概览
简要总结
Some nutraceuticals are often advised for their lipid lowering effects. Although many clinical trials have been conducted to assess their efficacy many doubts remain whether they could be considered an effective alternative to statins therapy.
The aim of this study was to evaluate the lipid lowering effects and the improvement of endothelial dysfunction in patients with hyperlipidemia, treated with a nutraceutical product (Armolipid Plus)
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males and females aged between 18 and 70
- •Total cholesterol levels > 220 mg/dl and LDL-Cholesterol > 130 mg/dl;
- •Patients with concomitant pathology such as diabetes, chronic heart failure, coronary artery disease, arterial hypertension, dysthyroidism, were admitted as long as stable in the previous three months
排除标准
- •Proven intolerance to an Armolipid Plus compound
- •Pregnant women, and women planning to conceive
- •Patients in therapy with lipid lowering drugs within the previous 6 weeks
- •Triglycerides concentration > 500mg/dl were excluded.
结局指标
主要结局
The primary outcome measure of this study was the percentage change from baseline of total cholesterol (C), LDL- cholesterol (LDL-C), HDL-cholesterol (HDL-C),and Triglycerides (Tg) plasma concentrations.
时间窗: 6 weeks
次要结局
- Secondary end point included improvement of endothelial dysfunction assessed by an echo flow mediated distribution test.(6 weeks)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
Combined Effects of Bioactive Compounds in Lipid ProfileLow-density-lipoprotein-typeElevated TriglyceridesHyperlipidemiaNCT01562080Rottapharm Spain118
已完成
不适用
The Antihypercholestrolemic Effect of a Combined Nutritional Supplementation of Standardized Extracts of Amla, Walnut, Red Yeast Rice and OliveHyperlipidemiaNCT06002893Liaquat University of Medical & Health Sciences221
已完成
不适用
Efficacy Study on the Lipid-lowering Effect of Plant Sterols and Fish OilHealthyMildly Elevated Cholesterol LevelsNCT01313988Unilever R&D332
已完成
2 期
Investigation of the effects of supplementation with curcuminoids in subjects with metabolic syndromeMetabolic syndromeJPRN-UMIN000018339Clinical Trial Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran100
已完成
3 期
Lipid Research Clinics Coronary Primary Prevention Trial (CPPT)Cardiovascular DiseasesCoronary DiseaseHeart DiseasesMyocardial IschemiaNCT00000488National Heart, Lung, and Blood Institute (NHLBI)