A randomized, placebo-controlled, double blind volunteer study into the effect of milk ingredients on gastroenteritis caused by an attenuated E. coli. - MIRAGE

Arla Foods Ingredients Group P/S0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Healthy male subjects, aged 18-55 yrs, living in the Ede/Wageningen neighbourhood - Informed consent -Availability of internet connection - Willingness to replace habitual dairy product intake with the supplied lowcalcium soy products - Willingness to abstain from products with high amounts of prebiotic fibers and from products with probiotics (except for the supplied one) starting 1 month prior to study start - Willingness to give up blood donation from 1 month before the start of the experiment and during the entire experimental period.

•Current or previous underlying disease of the GI tract - Allergy to milk products or lactose intolerance (selfreported)- Allergy to soy products (self-reported) - Use of antibiotics, norit, laxatives (up till 6 months prior to inclusion), cholestyramine, acid burn inhibitors or
•immune suppressive (up till 3 months prior to inclusion), and pre- and probiotics (up till 1 month prior to inclusion)- High titer serum antibodies against ETEC (10 ml blood sample collected at screening). - Vegetarians - Vegans - Heavy alcohol use (>4 consumptions/day or >20/week) -Drug use

发起方

Arla Foods Ingredients Group P/S