The Prevalence of a Low Ankle-Brachial Index in Patients With Acute Cerebral Ischemic Event.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- ABI
研究概览
简要总结
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.
The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke.
详细描述
Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.
The ABI is a non-invasive tool useful for the diagnosis of LEAD. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke. Significant ICAS is prevalent among patients having LEAD. Acute ischemic stroke due to significant ICAS has poor prognosis.
Patients with LEAD may be a suitable subgroup for screening for ICAS using duplex scanning.
Estimating the relationship between cerebral ischemic event and the ABI value could help better guide preventive and risk reduction strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute ischemic stroke or transient ischemic attack of anterior circulation
- •Consent of patient
排除标准
- •primary intracranial hemorrhage,
- •venous sinus thrombosis,
- •unconsciousness,
- •intubation,
- •inability to provide and write a consent application form.
结局指标
主要结局
ABI
时间窗: 7 days
Prevalence of a low ankle-brachial index (ABI) in patients with acute cerebral ischemic event
次要结局
- ABI/ICAS(7 days)
研究者
Pawel Sokal
Paweł Sokal
Jan Biziel University Hospital No 2 in Bydgoszcz