Evaluation of the Metabolic and Clinical Effects of Intraoperative Hyperchloremia in Holmium Laser Enucleation of Prostate (HoLEP) Surgery.

Ankara City Hospital Bilkent0 个研究点目标入组 45 人开始时间: 2026年7月4日最近更新: 2026年6月18日

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Ankara City Hospital Bilkent
入组人数: 45

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.

详细描述

Although isotonic irrigation fluids used in HoLEP surgery reduce the risk of hyponatremia associated with TUR syndrome, high-volume fluid absorption may lead to hyperchloremia and subsequent metabolic acidosis. This prospective, observational, single-center study, conducted at Ankara Bilkent City Hospital, aims to identify early markers of this condition to optimize perioperative management.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: Male
接受健康志愿者: 是

入选标准

•Patients scheduled for elective HoLEP surgery.
•Patients providing written informed consent

排除标准

•Preoperative metabolic acidosis.
•Advanced renal failure.
•Emergency surgery.
•Missing data.

研究者

发起方

Ankara City Hospital Bilkent

申办方类型

Other

责任方

Principal Investigator

主要研究者

Betül Güven

Assos prof

Ankara City Hospital Bilkent

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