Reducing Inappropriate Prescribing of Antibiotics by Primary Care Clinicians
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 170
- 试验地点
- 2
- 主要终点
- Reduction in the rate of broad-spectrum antibiotic prescribing for targeted conditions for which narrow-spectrum antibiotic therapy is indicated
研究概览
简要总结
The purpose of the study is to determine if physician education coupled with audit and feedback of antibiotic prescribing can improve antibiotic prescribing by primary care clinicians.
详细描述
Using a large, diverse pediatric primary care network sharing a comprehensive electronic health record (EHR), a cluster-randomized trial will be performed to determine the effectiveness of an outpatient antimicrobial stewardship bundle, including treatment guidelines coupled with audit and feedback of physician prescribing, to curb inappropriate antibiotic prescribing for respiratory tract infections.
Aim 1: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on antibiotic prescribing for conditions for which antibiotics are not indicated.
Hypothesis
Antimicrobial stewardship will decrease rates of antibiotic prescribing for conditions for which antibiotics are not indicated.
Aim 2: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on broad-spectrum antibiotic prescribing for conditions for which narrow-spectrum antibiotics are indicated.
Hypothesis
Antimicrobial stewardship will decrease the rate of broad-spectrum antibiotic prescribing for conditions for which narrow-spectrum antibiotics are indicated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Primary care pediatric practices within the CHOP Care Network
排除标准
- •Academic primary care pediatric practices within the CHOP Care Network
- •Providers entering a practice after the start of the intervention
- •Providers with less than 25 antibiotic prescriptions in the 6 months prior to the start of the intervention
研究组 & 干预措施
Antimicrobial Stewardship Bundle
An intervention "bundle" to reduce outpatient antibiotic use in children will include education, creation of and access to guidelines, and audit of and feedback on individual prescribing within the context of achievable benchmarks.
干预措施: Antimicrobial Stewardship Bundle (Behavioral)
Control
Control sites will be within strata to maintain balance of treatment arm within strata
结局指标
主要结局
Reduction in the rate of broad-spectrum antibiotic prescribing for targeted conditions for which narrow-spectrum antibiotic therapy is indicated
时间窗: from 20 months prior through 13 months post intervention
The primary outcome measure seeks to determine if the incorporation of treatment guidelines coupled with audit and feedback of physician prescribing can reduce the the rate of antibiotic prescribing for targeted conditions for which antibiotic therapy is not indicated.
次要结局
- The rate of antibiotic prescribing for targeted conditions for which antibiotic therapy is not indicated(from 20 months prior through 13 months post intervention)